Potential Therapeutic Approach of Melatonin against Omicron and Some Other Variants of SARS-CoV-2

Potential Therapeutic Approach of Melatonin against Omicron and Some Other Variants of SARS-CoV-2

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The Omicron variant (B.529) of COVID-19 caused disease outbreaks worldwide because of its contagious and diverse 6 Piece Sectional mutations.To reduce these outbreaks, therapeutic drugs and adjuvant vaccines have been applied for the treatment of the disease.However, these drugs have not shown high efficacy in reducing COVID-19 severity, and even antiviral drugs have not shown to be effective.Researchers thus continue to search for an effective adjuvant therapy with a combination of drugs or vaccines to treat COVID-19 disease.

We were motivated to consider melatonin as a defensive agent against SARS-CoV-2 because of its various unique properties.Over 200 scientific publications have shown the significant effects of melatonin in treating diseases, with strong antioxidant, anti-inflammatory, and immunomodulatory effects.Melatonin has a high safety profile, but it needs further clinical trials and experiments for use as a therapeutic agent against the Omicron variant of COVID-19.It might immediately be able to prevent the development of severe symptoms caused by the coronavirus and can reduce Sink Protector the severity of the infection by improving immunity.